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Scientist, Cytometric Profiling

Requisition ID: BIO005497

Merck Research Laboratories South San Francisco, a wholly owned subsidiary of Merck and Co., is focused on driving discovery research. Our new multi-disciplinary discovery research site offers state-of- the-art resources to explore the most promising science combined with Merck's world-class R&D expertise in small molecules and biologics. Located within the heart of the Bay area's biomedical community, research conducted in our new laboratories spans exploratory biology through early clinical development and is an integral part of Merck's powerful world-class network of drug and vaccine discovery.

At Merck, we are inspired by the belief that a research-driven enterprise dedicated to scientific excellence can create medicines and vaccines that save and improve lives. Every employee is building on our proud legacy of scientific breakthrough. Our ability to impact the lives of patients worldwide depends on the integrity, creativity, humility and scientific acumen of our team. We are creating a diverse organization that is inspired by invention and founded on a culture of respect and collaboration. At Merck Research Labs South San Francisco, you'll have the opportunity to expand your knowledge and skills through collaboration with talented and dedicated colleagues while advancing your career.

We are seeking an enthusiastic scientist to join the Cytometric Profiling group and Flow Cytometry/FACS core facility at Merck Research Laboratories in South San Francisco. Candidates should have experience with flow cytometry theory and practice, especially with BD Biosciences instrumentation. Experience with cell sorting is also highly desired. This position requires the candidate to perform FACS core responsibilities such as daily instrument startup, shutdown, QC, and maintenance. Furthermore, the successful candidate will have good working knowledge of the hardware, fluidics, and optics involved with flow cytometers. In addition to these core activities, the candidate will conduct immunoprofiling of various human, non-human primate, and murine tissues by flow cytometry and/or cell sorting to support team efforts to develop early pipeline immunotherapies. The candidate will work with program team members as well as with other intradepartmental groups to contribute data for regulatory filings of the many new therapeutics entering the clinic. Importantly, this position requires a candidate who has excellent oral and written communication skills and who will enjoy working with a large group of scientists.


Education Minimum Requirement:
• Minimum of a BS/BA in Biology, Biochemistry, or relevant discipline plus 3-5 years of industry experience or MS/MA in Biology, Biochemistry, or relevant discipline plus 1-2 years of industry experience.

Required Experience and Skills**:
• Experience with Flow Cytometry, preferably with BD Biosciences flow cytometers and acquisition software (FACS Diva)
• Data analysis using FlowJo
• Cell biology or immunology background
• Excellent communication and interpersonal skills
• Proficiency with MS Office applications on the Windows operating system
• Must be able to lift a 20-Liter box of sheath fluid (~45 lbs. each)

Preferred Experience and Skills:
• Cell sorting (FACS)
• Cell preparation for single cell RNA-sequencing
• Ex vivo functional assays such as proliferation, phospho-flow, or intracellular cytokine staining
• New analytical methods such as tSNE, viSNE, CITRUS, FlowSOM, etc.
• Proficiency with TIBCO Spotfire

The quality of our team is essential to our success. We are creating a new and innovative approach to rewarding our employees and establishing a comprehensive value proposition. Our competitive compensation program and benefits are designed to support the wide range of goals, needs and lifestyles of our employees, and the people that matter the most in their lives. If you need an accommodation for the application process please email us at .

Merck & Co., Inc. Kenilworth, N.J., U.S.A. known as Merck in the United States and Canada, is a global health care leader with a diversified portfolio of prescription medicines, vaccines and animal health products. Today, we are building a new kind of healthcare company - one that is ready to help create a healthier future for us all.

Job: Biology-Discovery
Other Locations:
Employee Status: Regular
Travel: No
Number of Openings: 1
Shift (if applicable): N/A
Hazardous Materials: BSL2 Lab
Company Trade Name: Merck

Nearest Major Market: San Francisco
Nearest Secondary Market: Oakland

Scientist, Cytometric Profiling

South San Francisco, CA
Full Time

Published on 07/12/2019