Company OverviewCell Signaling Technology, Inc. (CST) is a private, family owned, worldwide leader in the development and commercialization of antibodies, assays and research tools. As a company of scientists for scientists, we have developed XMT® technology, a proprietary method to develop exceptional monoclonal antibodies, PTMScan®, a technology to discover protein post-translational modifications, and PhosphoSitePlus®, an online resource for investigation of post-translational modifications. We are passionate about our role in contributing to the life science industry's advancing of the human condition through accelerating the discovery and development of innovative therapies for human disease. We are fully committed to developing new research tools to help define the mechanisms underlying cell function and disease, thereby broadly accelerating progress in biomedical research and medicine. The role The Multiplex Assays Development team is growing, and we are looking for a highly motivated Senior Research Associate who is passionate about collaborating with a team of scientists to develop and commercialize complex novel technologies for visualizing biology. A successful candidate will have the opportunity to independently manage an inventory of therapeutically relevant human and mouse tissues, and perform multiplex immunofluorescence experiments, analyze data, and communicate results to the team. This cross-functional, team-oriented position requires strong organizational skills, exceptional attention to detail, and robust scientific communication skills.Our work is a wonderful blend of exciting science and beautiful art, and we love that! The ideal candidate should pride themselves on precise technical execution, find joy in discovery, thrive on a fun and dynamic team, and possess a creative and innovative spirit. You'll have the opportunity to.... Maintain the inventory of paraffin-embedded human tissues, including sample logging and management of associated clinical data, when applicable. Prepare paraffin-embedded animal tissues, syngeneic tumors, and xenografts in conjunction with the Animal Facility staff. Create tissue microarrays, perform tissue sectioning, and maintain associated equipment per established policies. Collaborate with team members to identify and refine tissue models that enable definitive characterization of antibody and assay performance. Independently perform multiplex immunofluorescence imaging experiments, analyze data, and communicate results to senior staff via presentation and written reports. Operate multispectral microscopes, high-throughput imaging equipment, and laboratory robotics (autostainers). Complete scientific and technical tasks on aggressive timelines, adapt to changing priorities, and manage complex and varied wet lab assignments. Research targets and synthesize primary literature to support or refute immunostaining results. Identify, analyze, and troubleshoot technical issues relating to assay development and new lot quality assurance/quality control. Engage directly with customers who seek technical assistance via phone and email. Proactively identify, evaluate, and champion new technologies and workflow solutions that will improve quality, efficiency, and/or scalability. Maintain accurate and complete laboratory documentation in appropriate systems and testing databases in accordance with CST quality systems requirements. Support our commercial organization through trainings, scientific writing, and generation of marketing collateral. Contribute to strategic projects that support and promote the scientific culture and values of CST. Engage in personal and professional development activities to ensure currency of own approaches and techniques. Adhere to safety procedures in and around the laboratory. Who you are and what you bring to the team.... You possess a Bachelor's degree in a Life Sciences focus area and 4-6 years of lab experience, or a Master's degree with 1-2 years of lab experience. You have first-hand experience developing and optimizing antibody-based assays. You are comfortable with researching, synthesizing, and reporting on topics and methods from primary literature. You have a conceptual understanding of western blot, flow cytometry, immunofluorescence, immunohistochemistry, and the interpretation of their results. You are proficient with MS Word, PowerPoint, Excel, Google Docs, and related applications. You possess a natural curiosity and have excellent organizational skills. You take initiative to complete your work in a detail-oriented manner. You have enthusiasm for and motivation to collaborate, and strong interpersonal skills. You pride yourself on being a strong communicator with excellent English verbal, written, and presentation skills. You thrive in a team environment, while having a proven track record of completing projects independently when provided with high-level direction. You pride yourself on commitment to integrity, quality, collaboration, and innovation. Ideally, you have: Previous experience with spectral imaging, whole slide scanning, and immunoassays, specifically immunofluorescence and immunohistochemistry. Previous experience with tissue preparation, paraffin embedding, tissue sectioning, and tissue microarray creation. Familiarity with Immunology and Cell Biology, including signal transduction pathways and a broad knowledge of cellular markers. Working familiarity with image analysis platforms like InForm, QuPath, Halo, and/or Visiopharm, and data science tools like Python, R, or Tableau. Experience developing products in a design-controlled environment What we offer.... At Cell Signaling Technology Ⓡ (CST Ⓡ ) we recognize that people will always be our most important asset. Providing a safe, inclusive, and stimulating working environment that understands the importance of diversity, human dignity and meaningful work is as important as establishing company policies that incorporate excellent health insurance and pay benefits. We recognize that development of people is the key to their happiness and thus ensure every employee has impactful discussions with their manager and develops actionable performance and professional development plans. Lastly, we are committed to engaging and supporting our employees in committees and philanthropy that benefit their local communities and environment through community investment programs. Benefits Medical (BCBS) and Dental (Delta Dental) plans paid at 90% Vision Insurance Life Insurance, Short and Long Term Disability Flexible Spending accounts 401(k) Plan with 6% match Tuition Reimbursement Generous PTO package Pet Insurance Employee Assistance Program Onsite Subsidized Cafeteria Free Parking Our number one priority is the health and safety of our employees, their families, our communities, partners and customers. In order to promote that safety and well-being, we require that all US-based employees be fully vaccinated against COVID-19 by their start date. Applicants who receive an offer of employment who can provide documentation that the vaccine is medically contraindicated, or who object to vaccination due to a sincerely held religious belief, may make a request for exemption. We will consider requests for reasonable accommodations consistent with our policy, and where we are able to provide such accommodations without undue hardship to the company.Cell Signaling Technology Ⓡ (CST Ⓡ ) is committed to providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, national origin, age, disability, genetic information, status as a veteran or as a member of the military or status in any group protected by applicable federal or state laws. AGENCIES All resumes submitted by search firms/employment agencies to any employee at Cell Signaling Technology Ⓡ (CST Ⓡ ) via email, the internet or in any form and/or method will be deemed the sole property of CST Ⓡ , unless such search firms/employment agencies were engaged by CST Ⓡ for this position and a valid agreement with CST Ⓡ is in place. In the event a candidate who was submitted outside of the CST Ⓡ agency engagement process is hired, no fee or payment of any kind will be paid.