Senior Research Scientist I/II
Seeking a highly motivated, creative, and collaborative individual with a strong passion for and dedication to the discovery of new life-saving medicines. The candidate will join our internal efforts focused on the research and development of novel treatment, prevention, and HIV cure therapeutics, including small molecule drugs, biologics, and vaccines. The successful candidate will work in a highly collaborative environment to support the discovery and optimization of novel small molecules for HIV treatment and prevention. Primary responsibilities will include conducting in vitro virology studies to characterize newly discovered molecules as well as designing and evaluating new targets and therapeutic approaches in a fast-paced team environment. The successful candidate would be expected to:
- Lead the HIV virology efforts on cross-functional research teams.
- Conduct a variety of anti-HIV assays in cell lines and primary cells.
- Conduct in-depth characterization of mechanisms of antiviral activity.
- Characterize in vitro resistance profiles of lead compounds and/or biologics.
- Implement new technologies and assay automation into the Virology group.
- Identify, evaluate, and support external collaborations that complement and/or expand research goals.
- Make effective use of literature and CROs to complement research activities.
- Directly manage scientists and/or research associates in a thoughtful manner.
- Develop, execute, and troubleshoot assays and provide experimental guidance and growth opportunities to direct reports.
- Regularly document research findings in electronic notebook entries.
- Effectively write/edit documents to support regulatory and IP submissions, research manuscripts and public disclosures.
- Potentially lead multidisciplinary research teams.
- Present regular research updates to project teams and R&D management.
Knowledge, Experience, and Skills
- PhD in molecular biology, virology, immunology, or relevant life science discipline.
- Minimum of 3-5 years post-PhD research experience, including industry experience, focused on innovative research in virology with proven achievements in industrial or academic settings.
- Strong level of understanding and expertise in virology, viral immunology, and/or drug discovery.
- Experience with a broad array of technologies and automation to support assay development and discovery research is highly desired.
- Hands-on experience and broad expertise in molecular biology, virology techniques, and cell culture including primary cell isolation and culture is required. Experience in assay development, ability to evaluate the quality of the data, recognize anomalous results, and interpret experimental outcomes is essential. Experience with immune cell functional assays including multi-color FACS and ELISA/Luminex is ideal.
- Prior experience managing direct reports.
- Excellent verbal communication and interpersonal skills. Ability to communicate effectively within the Virology group and multidisciplinary groups within Research.